Article
Tfh1 Cells in Germinal Centers During Chronic HIV/SIV Infection.
Frontiers in immunology - 1 Jan 2018
Velu Vijayakumar, Mylvaganam Geetha, Ibegbu Chris, Amara Rama Rao
Abstract excerpt
T follicular helper CD4 cells (Tfh) are essential for the development and maintenance of germinal center (GC) reactions, a critical process that promotes the generation of long-lived high affinity humoral immunity. It is becoming increasingly evident that GC-Tfh cells are heterogeneous in nature with some cellular characteristics associated with a Th1, Th2, and Th17 phenotype. Emerging studies suggest that GC-Tfh...
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