Article

Microglia aggregates define distinct immune and neurodegenerative niches in Alzheimer's disease hippocampus.

2024-12-09

Abstract excerpt

<title>Abstract</title> <p>In Alzheimer's disease (AD), microglia show strong associations with amyloid-β (Aβ) and tau pathology, forming cellular aggregates such as Aβ plaque-associated microglia (PaM). Using high-content neuropathology, we found another type of microglial aggregates, morphologically distinct and not associated with Aβ plaques, mainly localised in the pyramidal layer of the CA2/CA1 human hippoca...

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Literature Corpus work: 23f532a6-a855-539c-9ef9-ced434897fdf
DOI: 10.21203/rs.3.rs-5387511/v1

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