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Article

Comprehensive Genomic Dependency Landscape of Human Colon Cancer

2024-06-04

Abstract excerpt

<title>Abstract</title> <p>Identifying genetic dependencies in human colon cancer could help identify effective treatment strategies. Genome-wide CRISPR-Cas9 dropout screens have the potential to reveal genetic dependencies, some of which could be exploited as therapeutic targets using existing drugs. In this study, we comprehensively characterized genetic dependencies present in a colon cancer organoid avatar, a...

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Literature Corpus work
3f9e5d1c-3eeb-5319-9991-873d987e61cc
DOI
10.21203/rs.3.rs-4438536/v1
Open publication

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Comprehensive Genomic Dependency Landscape of Human Colon CancerDOI 10.21203/rs.3.rs-4438536/v1
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