Article

A Mesenchymal-like Program of Dormancy controlled by ZFP281 Serves as a Barrier To Metastatic Progression of Early Disseminated Cancer Cells

2021-01-18

Abstract excerpt

<title>Abstract</title> <p>Increasing evidence shows that cancer cells can disseminate from early-evolved primary lesions much earlier than the classical metastasis models predicted. It is thought that a state of early disseminated cancer cell (early DCC) dormancy can precede genetic maturation of DCCs and metastasis initiation. Here we reveal at single cell resolution a previously unrecognized role of mesenchyma...

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Literature Corpus work: 3f94703b-894a-593e-959f-ac1addcb1d7b
DOI: 10.21203/rs.3.rs-145308/v1

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