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Unveiling cancer dormancy: Intrinsic mechanisms and extrinsic forces

21 Apr 2024

Abstract excerpt

Tumor cells disseminate in various distant organs at early stages of cancer progression. These disseminated tumor cells (DTCs) can stay dormant/quiescent without causing patient symptoms for years or decades. These dormant tumor cells survive despite curative treatments by entering growth arrest, escaping immune surveillance, and/or developing drug resistance. However, these dormant cells can reactivate to...

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PMID: 38649107
DOI: 10.1016/j.canlet.2024.216899

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