Article

A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy

2021-06-22

Abstract excerpt

<title>Abstract</title> <p>Cancer cells disseminate from primary tumors and seed in distant organs, where they can remain dormant for many years before forming clinically detectable metastases. Little is known about how extracellular matrix (ECM) sensing and remodeling can induce and sustain dormancy of disseminated tumor cells (DTCs). Another unanswered question is whether dormant cells themselves are able to as...

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Literature Corpus work: 2bfaf974-0dc2-55fd-bfd5-1971cf8f253e
DOI: 10.21203/rs.3.rs-580847/v1

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