Article

Metastatic founder cell candidates resemble preimplantation embryonic blastomeres

2026-08-31

Abstract excerpt

Disseminated cancer cells (DCC) in non-metastatic carcinoma patient bone marrow (BM) are predictive of metastasis. Those detected by epithelial cytokeratin or EpCAM expression have poorly-characterized transcription profiles due to their extreme rarity: 1~2 cells per two million BM cells in every third non-metastatic patient. We here characterize the transcriptomes of DCCs. Single-cell RNA-sequencing (scRNA-seq) o...

Identifiers and source

Literature Corpus work: 765979b5-8c06-55f2-bcf0-c190fe17bbd2
DOI: 10.64898/2026.08.28.747818

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