Article

Solriamfetol enhances alertness and cognitive performance in mice

2025-01-02

Abstract excerpt

Solriamfetol [(R)-2-amino-3-phenylpropylcarbamate hydrochloride], a phenylalanine derivative initially developed as potential antidepressant, was shown by our group in 2009 to have potent, dose-dependent wake-promoting activity in mice. Solriamfetol (Sunosi ® ) is used since 2019 to counteract excessive daytime sleepiness (EDS) in patients with narcolepsy and obstructive sleep apnea (OSA). It has several advantag...

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Literature Corpus work: 3f931c65-489e-53c9-86db-d4348dd0ee1c
DOI: 10.1101/2025.01.02.631072

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