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Article

mCLAS adaptively rescues disease-specific sleep and wake phenotypes in neurodegeneration.

Sleep medicine - 1 Dec 2024

Dias Inês, Baumann Christian R, Noain Daniela

Abstract excerpt

Sleep alterations are hallmarks of prodromal Alzheimer's (AD) and Parkinson's disease (PD), with fundamental neuropathological processes of both diseases showing susceptibility of change upon deep sleep modulation. However, promising pharmacological deep sleep enhancement results are hindered by specificity and scalability issues, thus advocating for noninvasive slow-wave activity (SWA) boosting methods to...

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PMID: 39541605
DOI: 10.1016/j.sleep.2024.11.009

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