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Article

Postanesthetic effects of isoflurane on behavioral phenotypes of adult male C57BL/6J mice.

PloS one - 1 Jan 2015

Yonezaki Kumiko, Uchimoto Kazuhiro, Miyazaki Tomoyuki, Asakura Ayako, Kobayashi Ayako, Takase Kenkichi, Goto Takahisa

Abstract excerpt

Isoflurane was previously the major clinical anesthetic agent but is now mainly used for veterinary anesthesia. Studies have reported widespread sites of action of isoflurane, suggesting a wide array of side effects besides sedation. In the present study, we phenotyped isoflurane-treated mice to investigate the postanesthetic behavioral effects of isoflurane. We applied comprehensive behavioral test batteries...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25806517
DOI: 10.1371/journal.pone.0122118
PMCID: PMC4373903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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