Article

Conserved human effector Treg signature is reflected in transcriptomic and epigenetic landscape

2020-10-01

Abstract excerpt

Treg are critical regulators of immune homeostasis, and increasing evidence demonstrates that environment-driven Treg differentiation into effector (e)Treg is crucial for optimal functioning. However, human Treg programming under inflammatory conditions remains poorly understood. Here, we combine transcriptional and epigenetic profiling to identify the human eTreg core signature. Functional autoimmune inflammation...

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Literature Corpus work: 3f76fa6a-bf3d-5931-81c7-f9c562b6d546
DOI: 10.1101/2020.09.30.319962

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