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A multi-omics analysis of effector and resting treg cells in pan-cancer

14 Mar 2025

Abstract excerpt

Regulatory T cells (Tregs) are critical for maintaining the stability of the immune system and facilitating tumor escape through various mechanisms. Resting T cells are involved in cell-mediated immunity and remain in a resting state until stimulated, while effector T cells promote immune responses. Here, we investigated the roles of two gene signatures, one for resting Tregs ( FOXP3 and IL2RA ) and another for...

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PMID: 40088713
DOI: 10.1016/j.compbiomed.2025.110021

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