Article

Differential effects of PD-1 and PD-L1 immune checkpoint inhibition on cognition and anxiety-like behavior through γδT cells and tumor–dependent neuroinflammation

2026-06-03

Abstract excerpt

<title>Abstract</title> <p>Cancer-related cognitive impairment (CRCI) is increasingly recognized in patients with solid tumors and treated with immunotherapy but the mechanisms linking tumor immune status, systemic inflammation and neurocognitive dysfunction remain unclear. Here, we investigate in syngeneic immuno-desert (B16F10), immuno-excluded (B16F10 Ova) and immuno-inflamed (MC38) tumor-bearing immunocompete...

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Literature Corpus work: 3f60b51b-a679-5399-89d7-4c3794409d00
DOI: 10.21203/rs.3.rs-9519248/v1

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Differential effects of PD-1 and PD-L1 immune checkpoint inhibition on cognition and anxiety-like behavior through γδT cells and tumor–dependent neuroinflammationDOI 10.21203/rs.3.rs-9519248/v1Read

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