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Single-cell RNA-seq of heart reveals intercellular communication drivers of myocardial fibrosis in diabetic cardiomyopathy

31 Mar 2023

Abstract excerpt

Myocardial fibrosis is the characteristic pathology of diabetes-induced cardiomyopathy. Therefore, an in-depth study of cardiac heterogeneity and cell-to-cell interactions can help elucidate the pathogenesis of diabetic myocardial fibrosis and identify treatment targets for the treatment of this disease. In this study, we investigated intercellular communication drivers of myocardial fibrosis in mouse heart with...

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Share to Cardiac Fibrosis and Remodeling
Share to Cardiomyopathy and Myosin Studies
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PMID: 37010266
DOI: 10.7554/elife.80479

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