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Article

Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy.

American journal of physiology. Heart and circulatory physiology - 1 Jul 2013

Medford Heidi M, Porter Karen, Marsh Susan A

Abstract excerpt

Cardiac hypertrophy induced by pathological stimuli is regulated by a complex formed by the repressor element 1-silencing transcription factor (REST) and its corepressor mSin3A. We previously reported that hypertrophic signaling is blunted by O-linked attachment of β-N-acetylglucosamine (O-GlcNAc...

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Source

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Identifiers

PMID: 23624624
DOI: 10.1152/ajpheart.00135.2013
PMCID: PMC3727102

Genes

OGT
REST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23624624-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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