Article

A Rapid and Highly Efficient Genotyping Pipeline for Screening Gene Targeted Mouse Embryonic Stem Cells

2021-07-30

Abstract excerpt

<title>Abstract</title> <p>Gene targeting in mouse ES cells replaces or modifies genes of interest; conditional alleles, reporter knock-ins, and amino acid changes are common examples of how gene targeting is used. For example, enhanced green fluorescent protein or Cre recombinase is placed under the control of endogenous genes to define promoter expression patterns. The most important step in the process is to d...

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Literature Corpus work: 3f186e33-193d-50f7-b00b-fd2acb1300c4
DOI: 10.21203/rs.3.rs-748320/v1

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