Article

A protocol for locating and counting transgenic sequences from laboratory animals using a map-then-capture (MapCap) sequencing workflow: procedure and application of results

2022-01-19

Abstract excerpt

<h4>ABSTRACT</h4> Transgenic rodent models for human diseases have been widely used over the past 50 years and are a mainstay of many biomedical research programs. Oftentimes the sequence of the transgenic segment of DNA is carefully designed but incorporation of this DNA into the host genome is less well understood. Structural variation and insertional mutagenesis may occur at transgenic insertion sites. Here, w...

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Literature Corpus work: f796df32-1bdb-5e00-b453-8bf40169b25a
DOI: 10.1101/2022.01.13.476149

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A protocol for locating and counting transgenic sequences from laboratory animals using a map-then-capture (MapCap) sequencing workflow: procedure and application of resultsDOI 10.1101/2022.01.13.476149Read

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