Article
Establishing a Mouse Genotyping Core Facility Based on Automation, High-resolution Melting Analysis, and Purpose-developed MATLAB Applications for Sample Tracking, Data Analysis, and Report Generation.
Comparative medicine - 1 Aug 2024
Dafni Hagit, Levi Kohava, Eldad Miriam Chen, Shaul May, Oren Roni, Alyagor Liat, Stettner Noa, Harmelin Alon, Haffner-Krausz Rebecca
Abstract excerpt
An in-house genotyping facility should aim to be more cost-effective than outsourced service and more reliable than genotyping performed by short-term employees or students of individual research groups. Reliable genotyping allows efficient and economical management of mice colonies and promotes accurate and reproducible research results. Here we provide a detailed description of our approach to establishing a...
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