Article
Mouse mutants and phenotypes: accessing information for the study of mammalian gene function.
Methods (San Diego, Calif.) - 1 Apr 2011
Ringwald Martin, Eppig Janan T
Abstract excerpt
Recent advances in high-throughput gene targeting and conditional mutagenesis are creating new and powerful resources to study the in vivo function of mammalian genes using the mouse as an experimental model. Mutant ES cells and mice are being generated at a rapid rate to study the molecular and phenotypic consequences of genetic mutations, and to correlate these study results with human disease conditions....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.