Article

Seeing cells smell: Dynamic optical measurements of Ca <sup>2+</sup> and cAMP signaling from Olfactory Receptors transiently expressed in HEK293TN cells

2019-09-16

Abstract excerpt

<h4>ABSTRACT</h4> Olfactory receptors (ORs) constitute the largest family of G-protein coupled receptors. They are responsible for the perception of odor (olfaction) and also play important roles in other biological processes, including regulation of cell proliferation. Their increasing diagnostic and therapeutic potential, especially for cancer research, requests the ongoing development of methodologies that wou...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ecf3298-d80b-5ba0-8eae-ce5178fa227a
DOI: 10.1101/771261

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Seeing cells smell: Dynamic optical measurements of Ca <sup>2+</sup> and cAMP signaling from Olfactory Receptors transiently expressed in HEK293TN cellsDOI 10.1101/771261Read

Quantitative live-cell imaging of GPCR downstream signaling dynamicsSemantic proximity Read

GEQO biosensors for absolute analyte quantification in single cellsSemantic proximity Read

A rapid fluorogenic GPCR-β-arrestin interaction assay.Semantic proximity Read

The Theodore Bücher lecture. Investigating signal transduction with genetically encoded fluorescent probes.Semantic proximity Read

[G protein-coupled receptors in the spot light].Semantic proximity Read

Live-cell assays for cell stress responses reveal new patterns of cell signaling caused by mutations in rhodopsin, α-synuclein and TDP-43Semantic proximity Read

A Bioluminescent and homogenous assay for monitoring GPCR-mediated cAMP modulation and PDE activitySemantic proximity Read

"cAMP sponge": a buffer for cyclic adenosine 3', 5'-monophosphate.Semantic proximity Read

Quantitative assessment of constitutive G protein-coupled receptor activity with BRET-based G protein biosensorsSemantic proximity Read

A Scalable, Multiplexed Assay for Decoding Receptor-Ligand InteractionsSemantic proximity Read

Identification of Signal Transduction Pathways Used by Orphan G Protein-Coupled ReceptorsSemantic proximity Read

Endocytic sorting of CFTR variants monitored by single-cell fluorescence ratiometric image analysis (FRIA) in living cells.Semantic proximity Read