Article

Live-cell assays for cell stress responses reveal new patterns of cell signaling caused by mutations in rhodopsin, α-synuclein and TDP-43

2019-08-15

Abstract excerpt

<h4>ABSTRACT</h4> Many neurodegenerative diseases induce high levels of sustained cellular stress and alter a number of cellular processes. Genetically-encoded fluorescent biosensors are effective tools to examine neuronal activity and signaling in living cells. To examine how different mutations associated with neurodegenerative disease affect cell stress and signaling we created live-cell assays for ER-mediated...

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Literature Corpus work: 87b5a1bf-f190-591f-b7c4-4596394c65ad
DOI: 10.1101/735878

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