Article
[G protein-coupled receptors in the spot light].
Biologie aujourd'hui - 1 Jan 2013
Benleulmi-Chaachoua Abla, Wojciech Stefanie, Jockers Ralf
Abstract excerpt
G protein-coupled receptors (GPCRs), also known as seven transmembrane domain-spanning proteins (7TM), play an important role in tissue homeostasis and cellular and hormonal communication. GPCRs are targeted by a large panel of natural ligands such as photons, ions, metabolites, lipids and proteins but also by numerous drugs. Research efforts in the GPCR field have been rewarded in 2012 by the Nobel Price in...
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