Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Signal Transduction Pathways Used by Orphan G Protein-Coupled Receptors

1 Apr 2003

Abstract excerpt

The superfamily of GPCRs have diverse biological roles, transducing signals from a range of stimuli, from photon recognition by opsins to neurotransmitter regulation of neuronal function. Of the many identified genes encoding GPCRs, >130 are orphan receptors ( i.e., their endogenous ligands are unknown), and this subset represents putative novel therapeutic targets for pharmaceutical intervention in a variety of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hormonal Regulation and Hypertension
Share to Neuropeptides and Animal Physiology
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15090189
DOI: 10.1089/15406580360545053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Signal Transduction Pathways Used by Orphan G Protein-Coupled ReceptorsPMID 15090189Read ↗

<i>In vitro</i> profiling of orphan G protein coupled receptor (GPCR) constitutive activitySemantic proximity Read ↗

The Identification of Ligands at Orphan G-Protein Coupled ReceptorsSemantic proximity Read ↗

G protein-coupled receptors: dominant players in cell-cell communication.Semantic proximity Read ↗

The role of orphan G protein-coupled receptors in painSemantic proximity Read ↗

In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activitySemantic proximity Read ↗

GPCRs: The most promiscuous druggable receptor of the mankindSemantic proximity Read ↗

Advances in the molecular level understanding of G-protein coupled receptor.Semantic proximity Read ↗

G protein-coupled receptors: abnormalities in signal transmission, disease states and pharmacotherapy.Semantic proximity Read ↗

G‐protein‐coupled receptors: past, present and futureSemantic proximity Read ↗

Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction.Semantic proximity Read ↗

International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands.Semantic proximity Read ↗

Focus issue: Cracking the G protein-coupled receptor code.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.