Article
The Theodore Bücher lecture. Investigating signal transduction with genetically encoded fluorescent probes.
European journal of biochemistry - 1 Jun 2003
Pozzan Tullio, Mongillo Marco, Rudolf Rüdiger
Abstract excerpt
Ca2+ and cAMP are ubiquitous second messengers in eukaryotes and control numerous physiological responses ranging from fertilization to cell death induction. To distinguish between these different responses, their subtle regulation in time, space and amplitude is needed. Therefore, the characterization of the signalling process requires measurement of second messengers with tools of precise localization, high...
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