Article

Hyper-responsiveness to Warfarin in A Young Patient with The VKORC1 -1639GA/CYP2C9146 Genotype: A Case Report

2022-07-25

Abstract excerpt

<h4>Background: </h4> Warfarin is the most widely used oral anticoagulant; nevertheless, dosing of warfarin is problematic for clinicians worldwide. Inter-individual variability in response to warfarin is attributed to genetic as well as non-genetic factors. Pharmacogenomics studies have identified variants in CYP2C9 and VKORC1 genes as significant predictors of warfarin dose, however, phenotypes of rare variants...

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Literature Corpus work: 3eb2ee1a-2ee3-5481-a82e-9aee0369a086
DOI: 10.21203/rs.3.rs-1850539/v1

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