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Article

Influence of CYP2C9 and VKORC1 genotypes on the risk of hemorrhagic complications in warfarin-treated patients: a systematic review and meta-analysis.

International journal of cardiology - 9 Oct 2013

Yang Jie, Chen Yanming, Li Xiaoqi, Wei Xiaowen, Chen Xi, Zhang Lanning, Zhang Yuxiao, Xu Qiang, Wang Hongjuan, Li Yang, Lu Caiyi, Chen Wei, Zeng Changqing, Yin Tong

Abstract excerpt

BACKGROUND: The main challenge for warfarin anticoagulation is the risk for hemorrhagic complications. Although certain pharmacogenetic factors may explain the individual variabilities about the therapeutic warfarin dose requirement, the genetic factors to warfarin hemorrhagic complications due to over-anticoagulation are largely unknown. To interpret the potential role of warfarin-related genotypes on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23932037
DOI: 10.1016/j.ijcard.2013.07.151

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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