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Article

VKORC1 gene polymorphisms and adverse events in Croatian patients on warfarin therapy.

International journal of clinical pharmacology and therapeutics - 1 Nov 2015

Mandic Dario, Bozina Nada, Mandic Sanja, Samardzija Marina, Milostic-Srb Andrea, Rumora Lada

Abstract excerpt

OBJECTIVE: The objective was to determine the impact of VKORC1 polymorphisms on warfarin anticoagulant therapy (stable warfarin maintenance dose, time required to reach therapeutic dose and time spent in therapeutic range) and its adverse events (overanticoagulation and bleeding events, time to first overanticoagulation or bleeding event, and therapy for bleeding events) in Croatian patients. MATERIALS: Blood...

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Source

Identifiers

PMID: 26445138
DOI: 10.5414/CP202424

Genes

VKORC1

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