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In the Cis-Element CACCC-Box a Master Regulatory Element during Cardiovascular Disease? A Bioinformatics Approach from the Perspective of the Kruppel-Like Family of Transcription Factors

2024-03-14

Abstract excerpt

The CACCC-box motif emerges as a pivotal cis-regulatory element implicated in diverse developmental processes and diseases, particularly cardiovascular diseases (CVDs). This study centers on the intricate interplay between the CACCC-box and its binding proteins such as: the Krüppel-like family (KLF) of transcription factors as primary effectors in the context of CVDs. Our analysis was through a bioinformatics...

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Literature Corpus work: 3e873ce5-cfe4-5480-a655-7ba1232be7e2
DOI: 10.20944/preprints202403.0607.v2

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