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Article

The Kruppel-like transcription factor KLF13 is a novel regulator of heart development.

The EMBO journal - 1 Nov 2006

Lavallée Geneviève, Andelfinger Gregor, Nadeau Mathieu, Lefebvre Chantal, Nemer Georges, Horb Marko E, Nemer Mona

Abstract excerpt

In humans, congenital heart defects occur in 1-2% of live birth, but the molecular mechanisms and causative genes remain unidentified in the majority of cases. We have uncovered a novel transcription pathway important for heart morphogenesis. We report that KLF13, a member of the Krüppel-like family of zinc-finger proteins, is expressed predominantly in the heart, binds evolutionarily conserved regulatory...

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Source

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Identifiers

PMID: 17053787
DOI: 10.1038/sj.emboj.7601379
PMCID: PMC1630408

Genes

KLF13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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