Article
Gene expression and transcriptional regulation driven by transcription factors involved in congenital heart defects.
Irish journal of medical science - 1 Apr 2023
Mubeen Hira, Farooq Muhammad, Rehman Asif Ur, Zubair Muhammad, Haque Asma
Abstract excerpt
BACKGROUND: Congenital heart disease (CHD) is one of the most important birth defects caused by more than one mutated gene. Mutations in the genes could cause different types of congenital heart defects including atrial septal defect (ASD), tetralogy of Fallot (TOF), and ventricular septal defect (VSD). OBJECTIVES: Cardiac transcription factors are key players for heart development and are actively involved in...
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