Article

Genomics of primary chemoresistance and remission induction failure in pediatric and adult acute myeloid leukemia

2016-04-30

Abstract excerpt

Despite intense efforts, the cure rates of children and adults with AML remain unsatisfactory in large part due to resistance to chemotherapy. Whilst cytogenetic risk stratification proved valuable in identifying causes of therapy failure and disease relapse, cytogenetically normal AML remains the most prevalent disease type, with significant heterogeneity of clinical outcomes, including primary chemoresistance. U...

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Literature Corpus work: 3e7be738-1ea6-5f19-ada0-be5c97de5773
DOI: 10.1101/051177

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