Article
Next-Generation Sequencing-Based Genomic Profiling of Children with Acute Myeloid Leukemia.
The Journal of molecular diagnostics : JMD - 1 Aug 2023
Krizsán Szilvia, Péterffy Borbála, Egyed Bálint, Nagy Tibor, Sebestyén Endre, Hegyi Lajos László, Jakab Zsuzsanna, Erdélyi Dániel J, Müller Judit, Péter György, Csanádi Krisztina, Kállay Krisztián, Kriván Gergely, Barna Gábor, Bedics Gábor, Haltrich Irén, Ottóffy Gábor, Csernus Katalin, Vojcek Ágnes, Tiszlavicz Lilla Györgyi, Gábor Krisztina Mita, Kelemen Ágnes, Hauser Péter, Gaál Zsuzsanna, Szegedi István, Ujfalusi Anikó, Kajtár Béla, Kiss Csongor, Matolcsy András, Tímár Botond, Kovács Gábor, Alpár Donát, Bödör Csaba
Abstract excerpt
Pediatric acute myeloid leukemia (AML) represents a major cause of childhood leukemic mortality, with only a limited number of studies investigating the molecular landscape of the disease. Here, we present an integrative analysis of cytogenetic and molecular profiles of 75 patients with pediatric AML from a multicentric, real-world patient cohort treated according to AML Berlin-Frankfurt-Münster protocols....
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