Article

IL-17 sensitises sensory neurons and colonic afferents to noxious stimuli in a PI3K dependent manner

2025-04-21

Abstract excerpt

Managing visceral pain associated with gastrointestinal (GI) disease remains a significant challenge due to the gut-related side effects and contraindicated use of many commonly used painkillers in people with inflammatory bowel disease (IBD). Consequently, it is crucial to deepen our understanding of the mediators and mechanisms underlying inflammatory pain in people with IBD. To do this, we compared bulk RNA seq...

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Literature Corpus work: 3e735842-f7f7-5baf-bdfb-b7b316fde034
DOI: 10.1101/2025.04.16.649143

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IL-17 sensitises sensory neurons and colonic afferents to noxious stimuli in a PI3K dependent mannerDOI 10.1101/2025.04.16.649143Read

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