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L-Cells are the Functional Neuropod Cell in Human Gastrointestinal Tract and are Dysregulated in Inflammatory Bowel Disease (IBD)

2025-10-31

Abstract excerpt

Neuropod cells are a newly discovered type of enteroendocrine cell (EEC) that connect the gut and brain functionally into one circuit. In the mouse colon, neuropod cells express various peptide hormones, such as Pyy and Glp1, presynaptic proteins, and make synaptic contacts with sensory neurons. While their function is not fully elucidated, they play a significant role in relaying signals to the brainstem upon sen...

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Literature Corpus work
cb82a4ee-b42e-5f06-92fd-7f5e2bdb6b0e
DOI
10.1101/2025.10.30.685584
Open publication

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L-Cells are the Functional Neuropod Cell in Human Gastrointestinal Tract and are Dysregulated in Inflammatory Bowel Disease (IBD)DOI 10.1101/2025.10.30.685584
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