Article

Glucose metabolism reflects local atrophy and tau pathology in symptomatic Alzheimer’s disease

2021-03-12

Abstract excerpt

Posterior cortical hypometabolism measured with [ 18 F]-Fluorodeoxyglucose (FDG)-PET is a well-known marker of Alzheimer’s disease-associated neurodegeneration, but its associations with underlying neuropathological processes are unclear. We assessed the relative contributions of three potential mechanisms causing hypometabolism in the retrosplenial and inferior parietal cortices: local molecular (amyloid and tau)...

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Literature Corpus work: 3e6c8042-c9a6-54df-ba71-ed8d69c79d09
DOI: 10.1101/2021.03.08.21252999

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