Article

Mesoscale medial temporal lobe connectivity patterns relate to tau pathology and memory in older adults

2026-08-21

Abstract excerpt

The medial temporal lobe (MTL) is crucial for episodic memory. Tau pathology is a hallmark of Alzheimer's disease (AD) and accumulates in layer-specific patterns in the MTL during aging. It is, however, unclear whether early AD pathology relates to mesoscale network signatures distinct from non-pathological aging. To address this gap, we acquired 7 Tesla submillimeter-resolution resting-state fMRI, plasma-based AD...

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Literature Corpus work: 140f8ccc-2790-5a13-9455-00fbef19b50c
DOI: 10.64898/2026.08.18.745399

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