Article

Differential Brain Atrophy Patterns and Neurogenetic Profiles in Cognitively-Defined Alzheimer’s Disease Subgroups

2020-08-04

Abstract excerpt

Elucidating mechanisms underlying the clinical heterogeneity observed among individuals with Alzheimer’s disease (AD) is key to facilitate personalized treatments. We categorized 679 individuals with AD into subgroups based on a relative impairment in one cognitive domain (i.e. AD-Memory, AD-Executive-Functioning, AD-Language and AD-Visuospatial-Functioning). We compared atrophy patterns derived from MRI and ident...

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Literature Corpus work: 18a1ffe5-4b0e-50f7-8fa7-50605f9d116c
DOI: 10.1101/2020.08.04.235762

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