Article

Amyloid beta acts synergistically as a pro-inflammatory cytokine

2020-09-29

Abstract excerpt

<h4>SUMMARY</h4> The amyloid beta (Aβ) peptide is believed to play a central role in Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder. However, the natural, evolutionarily-selected functions of Aβ are incompletely understood. Here, we report that nanomolar concentrations of Aβ act synergistically with known cytokines to promote pro-inflammatory activation in primary human astrocyte...

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Literature Corpus work: 3e6af489-3e37-58e9-9e7f-2472537fd527
DOI: 10.1101/2020.09.28.316927

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