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The Hidden Role of Non-Canonical Amyloid β Isoforms in Alzheimer’s Disease

29 Oct 2022

Abstract excerpt

Recent advances have placed the pro-inflammatory activity of amyloid β (Aβ) on microglia cells as the focus of research on Alzheimer’s Disease (AD). Researchers are confronted with an astonishing spectrum of over 100 different Aβ variants with variable length and chemical modifications. With the exception of Aβ1-42 and Aβ1-40, the biological significance of most peptides for AD is as yet insufficiently...

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PMID: 36359817
DOI: 10.3390/cells11213421

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