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Article

Mitochondrial replacement: from basic research to assisted reproductive technology portfolio tool-technicalities and possible risks.

Molecular human reproduction - 1 Jan 2015

Cree Lynsey, Loi Pasqualino

Abstract excerpt

Mitochondrial DNA (mtDNA) mutations are a relatively common cause of progressive disorders that can be severe or even life-threatening. There is currently no cure for these disorders; therefore recent research has been focused on attempting to prevent the transmission of these maternally inherited mutations. Here we highlight the challenges of understanding the transmission of mtDNA diseases, discuss current...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25425606
DOI: 10.1093/molehr/gau082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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