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Article

Three-parent babies: Mitochondrial replacement therapies.

JBRA assisted reproduction - 1 May 2020

Farnezi Hana Carolina Moreira, Goulart Ana Carolina Xavier, Santos Adriana Dos, Ramos Mariana Gontijo, Penna Maria Lectícia Firpe

Abstract excerpt

The mitochondria are intracellular organelles, and just like the cell nucleus they have their own genome. They are extremely important for normal body functioning and are responsible for ATP production - the main energy source for the cell. Mitochondrial diseases are associated with mutations in mitochondrial DNA and are inherited exclusively from the mother. They can affect organs that depend on energy...

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Identifiers

PMID: 32073245
DOI: 10.5935/1518-0557.20190086
PMCID: PMC7169912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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