Article

Stable transplantation of human mitochondrial DNA by high-throughput, pressurized mitochondrial delivery

2020-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Generating mammalian cells with specific mtDNA-nDNA combinations is desirable but difficult to achieve and would be enabling for studies of mitochondria-nucleus communication and coordination in controlling cell fates and functions. We developed ‘MitoPunch’, a force-actuated mitochondrial transfer device, to deliver isolated mitochondria into numerous target mammalian cells simultaneousl y . Mi...

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Literature Corpus work: bfdfbbdc-5616-5bcf-a2f3-81bad0b04dc6
DOI: 10.1101/2020.09.15.298174

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