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Article

Identification of neoantigens in esophageal adenocarcinoma

2022-05-04

Abstract excerpt

Esophageal adenocarcinoma (EAC) has a relatively poor long-term survival and limited treatment options. Promising targets for immunotherapy are short peptide neoantigens containing tumor mutations, presented to cytotoxic T-cells by human leukocyte antigen molecules (HLA). Despite an association between putative neoantigen abundance and therapeutic response across cancers, immunogenic neoantigens are challenging to...

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Literature Corpus work
e4c1e058-3fc7-5f7c-bb75-de1a354ec82e
DOI
10.1101/2022.05.04.490567
Open publication

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Identification of neoantigens in esophageal adenocarcinomaDOI 10.1101/2022.05.04.490567
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