Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets.

BioMed research international - 1 Jan 2020

Chen Chao, Liu Songming, Qu Ruokai, Li Bo

Abstract excerpt

This study was aimed at investigating the mutations in colorectal cancer (CRC) for recurrent neoantigen identification. A total of 1779 samples with whole exome sequencing (WES) data were obtained from 7 published CRC cohorts. Common HLA genotypes were used to predict the probability of neoantigens at high-frequency mutants in the dataset. Based on the WES data, we not only obtained the most comprehensive CRC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Antigens, Neoplasm
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Immunotherapy

Share to INDEL Mutation

Share to Mutation Rate

Share to Peptides

Source

Open in PubMed Open full text

Identifiers

PMID: 32733937
DOI: 10.1155/2020/2861240
PMCID: PMC7383341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets.PMID 32733937Read ↗

Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy TargetsSemantic proximity Read ↗

The common neoantigens in colorectal cancer are predicted and validated to be presented or immunogenicSemantic proximity Read ↗

[A method of screening highly common neoantigens with immunogenicity in colorectal cancer based on public somatic mutation library].Semantic proximity Read ↗

Neoantigens Derived from Recurrently Mutated Genes as Potential Immunotherapy Targets for Gastric CancerSemantic proximity Read ↗

Mutated genes on ctDNA detecting postoperative recurrence presented reduced neoantigens in primary tumors in colorectal cancer cases.Semantic proximity Read ↗

A Comprehensive Survey of Mutations in Oesophageal Carcinoma Reveals Recurrent Neoantigens as Potential Immunotherapy TargetsSemantic proximity Read ↗

Immunogenicity of Neoantigens in Colorectal Cancer: Potential Influence of Tumor Mutation Burden, Stages, and MetastasisSemantic proximity Read ↗

A Comprehensive Survey of Genomic Alterations in Gastric Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets.Semantic proximity Read ↗

Identification of public neoantigens with broad HLA class I coverage as candidates for off-the-shelf cancer vaccine development in colorectal cancer.Semantic proximity Read ↗

Evolving neoantigen profiles in colorectal cancers with DNA repair defectsSemantic proximity Read ↗

Whole-Exome Sequencing to Screen Personal Neoantigens With High Immunogenicity in Patients With Microsatellite Stability (MSS)-Advanced Colorectal Cancer.Semantic proximity Read ↗

The Role of Neoantigens in Cancer ImmunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.