Article

Comparison of Single-cell Long-read and Short-read Transcriptome Sequencing of Patient-derived Organoid Cells of ccRCC: Quality Evaluation of the MAS-ISO-seq Approach

2024-03-15

Abstract excerpt

Single-cell RNA sequencing is used in profiling gene expression differences between cells. Short-read sequencing platforms provide high throughput and high-quality information at the gene-level, but the technique is hindered by limited read length, failing in providing an understanding of the cell heterogeneity at the isoform level. This gap has recently been addressed by the long-read sequencing platforms that pr...

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Literature Corpus work: 3e15e1c2-5968-5b4c-baf1-4bf0f3424247
DOI: 10.1101/2024.03.14.584953

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