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Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells

2023-03-20

Abstract excerpt

The protein diversity of mammalian cells is determined by arrays of isoforms from genes. Genetic mutation is essential in species evolution and cancer development. Accurate Long-read transcriptome sequencing at single-cell level is required to decipher the spectrum of protein expressions in mammalian organisms. In this report, we developed a synthetic long-read single-cell sequencing technology based on LOOPseq te...

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Literature Corpus work
d6fe8130-d4ab-5656-abdc-13fcfcf05c87
DOI
10.1101/2023.03.16.532991
Open publication

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Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cellsDOI 10.1101/2023.03.16.532991
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