Article

Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids

2024-03-17

Abstract excerpt

Splicing is often dysregulated in cancer, leading to alterations in the expression of canonical and alternative splice isoforms. This complex phenomenon can be revealed by an in-depth understanding of cellular heterogeneity at the single-cell level. Recent advances in single-cell long- read sequencing technologies enable comprehensive transcriptome sequencing at the single-cell level. In this study, we have genera...

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Literature Corpus work: 21640500-ce3f-5e59-99b5-f868704ffb18
DOI: 10.1101/2024.03.15.585271

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