Article

Exome-capture RNA-sequencing of decade-old breast cancers and matched decalcified bone metastases identifies clinically actionable targets

2017-03-26

Abstract excerpt

<h4>ABSTRACT</h4> Bone metastases (BoM) are a significant cause of morbidity in patients with Estrogen-receptor (ER)-positive breast cancer, yet characterizations of human specimens are limited. In this study, exome-capture RNA-sequencing (ecRNA-seq) on aged (8-12 years), formalin-fixed paraffin-embedded (FFPE) and decalcified cancer specimens was first evaluated. Gene expression values and RNA-seq quality metric...

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Literature Corpus work: 3e11a0ef-e9d2-5bc4-aee6-580e44afcefc
DOI: 10.1101/120709

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