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Transcriptomic landscape of breast cancers through mRNA sequencing

14 Feb 2012

Abstract excerpt

Breast cancer is a heterogeneous disease with a poorly defined genetic landscape, which poses a major challenge in diagnosis and treatment. By massively parallel mRNA sequencing, we obtained 1.2 billion reads from 17 individual human tissues belonging to TNBC, Non-TNBC, and HER2-positive breast cancers and defined their comprehensive digital transcriptome for the first time. Surprisingly, we identified a high...

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Ferroptosis and cancer prognosis
Molecular Biology Techniques and Applications
RNA modifications and cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22355776
DOI: 10.1038/srep00264

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