Article

Investigating the contribution of AMPK regulation to physiology and lifespan in C. elegans

2021-01-01

Abstract excerpt

Life expectancy increased dramatically during the 20th century and gave rise to a variety of age-related diseases which affect modern society. Recent studies investigating the relationship between energy homeostasis and longevity imply that nutrient-sensing pathways are important for determining lifespan. AMP-activated protein kinase (AMPK) is a key metabolic regulator which responds to changes in the AMP:ATP rati...

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Literature Corpus work: 3dfc3cb6-29ac-5d79-826a-de26fe77c354
DOI: 10.22024/unikent/01.02.87521

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